Telomeres Terminating with Long Complex Tandem Repeats
نویسندگان
چکیده
منابع مشابه
Resolving complex tandem repeats with long reads
MOTIVATION Resolving tandemly repeated genomic sequences is a necessary step in improving our understanding of the human genome. Short tandem repeats (TRs), or microsatellites, are often used as molecular markers in genetics, and clinically, variation in microsatellites can lead to genetic disorders like Huntington's diseases. Accurately resolving repeats, and in particular TRs, remains a chall...
متن کاملCharacterization of short tandem repeats from thirty-one human telomeres.
Completion of genetic and physical maps requires markers from the ends (telomeres) of every human chromosome. We have searched for short tandem repeats (microsatellites) in cosmid and P1 clones and generated 661 sequence-tagged sites (STS) from the terminal 300 kb of 31 human chromosome ends. PCR assays were successfully designed for 58 microsatellites and mapped both genetically and on radiati...
متن کاملTRDB—The Tandem Repeats Database
Tandem repeats in DNA have been under intensive study for many years, first, as a consequence of their usefulness as genomic markers and DNA fingerprints and more recently as their role in human disease and regulatory processes has become apparent. The Tandem Repeats Database (TRDB) is a public repository of information on tandem repeats in genomic DNA. It contains a variety of tools for repeat...
متن کاملTandem Repeats in Prokaryotic Genomes
1 Department of Information Science, Graduate School of Science, Hirosaki University, 3 Bunkyo-cho, Hirosaki 036-8561, Japan 2 Department of Electronic and Information System Engineering, Faculty of Science and Technology, Hirosaki University, 3 Bunkyo-cho, Hirosaki 036-8561, Japan 3 Graduate School of Mathematics, Nagoya University, Chikusa-ku, Nagoya 464-8602, Japan 4 Protonic NanoMachine Pro...
متن کاملTandem repeats: two different approaches
where the pattern composed by the three bases CGG in the left sequence is transformed in five identical and adjacent copies. Additional mutational laws can cause mismatch between the bases of the pattern and the bases of the repeated copies, for this reason sometimes there is no an exact repetition of the pattern but there is an approximate repetition in which every copies of the pattern is qui...
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ژورنال
عنوان ژورنال: Hereditas
سال: 2004
ISSN: 0018-0661
DOI: 10.1111/j.1601-5223.1997.00175.x